Prediction of pathogen positive-culture results in acute poisoning patients with suspected aspiration

Purpose: This study sought to compare the characteristics of patients with pathogen-positive and negative cultures, investigate factors predicting culture results in acute poisoning suspected aspiration. Methods: Consecutive admitted an intensive care unit between January 2016 December 2018 were retrospectively studied. Respiratory specimens collected from enrolled at time We compared analyzed causative pathogens. Results: Among 526 patients, 325 showed no clinical features that could be attributed aspiration, 201 had suggestive Of these, 113 culture, 61 negative, 27 contained poor-quality sputum. In univariate analysis, a positive longer ingestion (p=0.01), faster heart rate higher partial pressure arterial oxygen fraction inspired (PaO2/FiO2) (p=0.02) than culture. Multivariate analysis demonstrated PaO2/FiO2 (adjusted odd ratio, 1.005; 95% confidence interval [CI], 1.002-1.008; p=0.005) was significant risk factor for The area under receiver operating characteristic curve 0.591 (95% CI, 0.510-0.669, p=0.05). Gram-negative pathogens (GNPs) predominant least one GNP observed 84 (73.3%) among those pathogen Conclusion: failed find any associated results. Antibiotics cover GNPs considered when deciding initial antibiotic regimen